Premium
Investigations on the Chemistry of Berbanes, XIII. Selective Reduction of Normal ‐, Allo ‐, Pseudo ‐, and Epiallo ‐Depyrrolo‐Yohimbone Analogues
Author(s) -
Tóth István,
Bozsár Gabriella,
Szabó Lajos,
Tamás József,
BaitzGács Eszter,
Szántay Csaba
Publication year - 1987
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198719870867
Subject(s) - chemistry , reduction (mathematics) , fragmentation (computing) , selective reduction , ring (chemistry) , alcohol , selective catalytic reduction , medicinal chemistry , catalysis , stereochemistry , organic chemistry , geometry , mathematics , computer science , operating system
The reduction of normal‐, allo‐, epiallo‐ , and pseudo ‐berbanones were studied under different conditions. Reduction with Na/alcohol always led to the thermodynamically controlled products while catalytic and NaBH 4 reduction resulted almost exclusively in the kinetically controlled compounds. An interesting correlation was observed between the MS fragmentation and ring C/D stereochemistry.