Premium
13 C‐NMR and CD Spectroscopy with Isochromanquinones – Potent Methods to Determine the Stereochemistry and the Tautomeric Equilibrium in This Group of Antibiotics
Author(s) -
Krone Bernd,
Zeeck Axel
Publication year - 1987
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198719870823
Subject(s) - tautomer , chemistry , actinorhodin , interpretation (philosophy) , nuclear magnetic resonance spectroscopy , group (periodic table) , antibiotics , computational chemistry , spectroscopy , stereochemistry , organic chemistry , polyketide , biochemistry , physics , enzyme , quantum mechanics , computer science , biosynthesis , programming language
The isochromanquinones of the naphthocyclinone and actinorhodin series get a thorough interpretation of their 13 C‐NMR and CD spectra. By improving these two methods the difficult structural problems in the whole group of these antibiotics will be solved easily and reliably. In addition, the equilibrium of the naphthazarin tautomers 1–4 (R 3 = H) in solution can be described more exactly for the first time.