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Synthesis of Vinca Alkaloids and Related Compounds, XXXVI. A Simple Synthesis of Some D ‐Noreburnamenine Derivatives
Author(s) -
Kalaus György,
Galambos János,
KajtárPeredy Mária,
Tamás JÓZsef,
Szabó Lajos,
Sápi János,
Sźantay Csaba
Publication year - 1987
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198719870822
Subject(s) - chemistry , vinca , enamine , combinatorial chemistry , organic chemistry , stereochemistry , catalysis , botany , biology
Reaction of the enamine 5 with α‐bromoacrylic esters or α‐chloroacrylonitrile and subsequent reduction with NaBH 4 yielded the pentacyclic D ‐noreburnamenine derivatives 8–10 or 11–14 , respectively.
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