Chirale Isoprenylether aus 3‐Ethoxy‐2‐methylacrolein durch vinyloge Umesterung und Wittig‐Alkenylierung

Chiral Isoprenyl Ethers from 3‐Ethoxy‐2‐methylacrolein by Vinylogous Transesterification and Wittig Alkenylation Chiral isoprenyl ethers 5 as potential starting materials for enantioselective syntheses of cyclic terpenes are shown in a model reaction to be prepared by vinylogous transesterification of 3‐ethoxy‐2‐methylacrolein ( 1 ) with chiral alcohols such as ( R )‐ and ( S )‐1,2‐ O ‐isopropylideneglycerol 2 and subsequent Wittig alkenylation of the resulting chiral 3‐alkoxy‐2‐methylacroleins 3 .