Premium
Synthese von Dipeptid‐triestern mit Phosphonoglycin als N‐terminaler Komponente
Author(s) -
Köhler Burkhard,
Schöllkopf Ulrich
Publication year - 1987
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198719870320
Subject(s) - chemistry , phosphonate , dipeptide , stereochemistry , hydrolysis , component (thermodynamics) , organic chemistry , peptide , biochemistry , thermodynamics , physics
Synthesis of Dipeptide Triesters with Phosphonoglycine as N‐terminal Component Starting with diethyl (isocyanomethyl)phosphonate ( 1 ) and methyl α‐isocyanatoalkanoates 3 a series of dipeptide triesters 5 was synthesized. As found with 5a , hydrolysis of 5 to give the dipeptides 6 with (phosphono)Gly as N‐terminal component is possible, but 6 could not be obtained in pure form.