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Synthese von 2,3‐Dihydro‐1 H ‐pyrrolizin‐7‐carbaldehyd, dem Sexualpheromon Danaidal
Author(s) -
Röder Erhard,
Wiedenfeld Helmut,
Bourauel Thomas
Publication year - 1986
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198619860915
Subject(s) - dehydrogenation , chemistry , sulfur , carboxylate , medicinal chemistry , stereochemistry , organic chemistry , catalysis
Synthesis of 2,3‐Dihydro‐1 H ‐pyrrolizine‐7‐carbaldehyde, the Sex Pheromone Danaidal Danaidal ( 4 ) can easily be obtained in high yields from ethyl 2,3,5,6‐tetrahydro‐1 H ‐pyrrolizine‐7‐carboxylate ( 1 ) via sulphur dehydrogenation or MnO 2 oxidation, subsequent reduction to dehydrosupinidine ( 3 ), and further oxidation to the desired title compound 4 .
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