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Thiazolsynthesen mit N ‐Cyanimidsäureestern oder 3‐Cyanisoharnstoffen und Thioglycolsäurederivaten
Author(s) -
Ried Walter,
Kuhnt Dietmar
Publication year - 1986
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198619860417
Subject(s) - thioglycolic acid , chemistry , medicinal chemistry , amide , organic chemistry
Thiazoles from N ‐Cyanoimidates or 3‐Cyanoisoureas and Thioglycolic Acid Derivatives Novel thiazoles 3a – g , 4a – d are synthesized from N ‐cyanoimidates and 3‐cyanoisoureas of type 1a – m and thioglycolic acid methyl ester ( 2a ) as well as the amide ( 2b ). The limitations of the reaction are outlined. The products are further converted into thiazolo[4,5‐ d ]pyrimidines 6a – d and thiazolo [4,5‐ d ]‐1,2,3‐triazinones 7a – c .