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Synthesis of Yohimbines, 5. Enantioselective Total Synthesis of Yohimbine and β‐Yohimbine Antipodes
Author(s) -
Blaskó Gábor,
Knight Hector,
Honty Katalin,
Szántay Csaba
Publication year - 1986
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198619860407
Subject(s) - yohimbine , enantioselective synthesis , chemistry , antipodes , stereochemistry , organic chemistry , catalysis , biochemistry , receptor , antagonist , geodesy , geography
Both, natural and non‐natural antipodes of yohimbine ( 1 ) and β‐yohimbine ( 2 ) have been synthesized from the tetracyclic keto ester 12 using second order asymmetric transformation in its resolution step.