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Phosphorus Pentoxide in Organic Synthesis, XVIII. Phosphorus Pentoxide and Secondary Amine Mixtures in a New Synthesis of N 6 , N 6 ‐Dialkyl‐ and N 6 ‐Alkyl, N 6 ‐aryl‐9 H ‐purin‐6‐amines
Author(s) -
ElBayouki Khairy A. M.,
Nielsen Flemming E.,
Pedersen Erik B.
Publication year - 1985
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198519850613
Subject(s) - phosphorus pentoxide , chemistry , triethylamine , amine gas treating , pentoxide , phosphorus , hydrochloride , medicinal chemistry , organic chemistry , inorganic chemistry , vanadium
A series of N 6 , N 6 ‐disubstituted 9 H ‐purin‐6‐amines 2a – i was prepared from 5‐acetamido‐6‐amino‐2‐methylpyrimidin‐4(3 H )‐one ( 1 ) and a secondary amine or its hydrochloride in the presence of phosphorus pentoxide and triethylamine hydrochloride.