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Zur Chemie der 1,2,4‐Triazine, X. Synthese von 1,2,4‐Triazino[5,6‐ b ][1,4]benzodiazepinonen
Author(s) -
Neunhoeffer Hans,
Hansa Jendy,
Hammann Heinz
Publication year - 1985
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198519850326
Subject(s) - chemistry , triazine , medicinal chemistry , stereochemistry , polymer chemistry
Chemistry of 1,2,4‐Triazines, X. – Synthesis of 1,2,4‐Triazino[5,6‐ b ][1,4]benzodiazepinones 6‐Amino‐1,2,4‐triazin‐5(2 H )‐thiones 4a – f react with isatoic anhydride ( 5 ) to give 1,2,4‐triazino‐[5,6‐ b ][1,4]benzodiazepinones 6a – f . By reaction of 6‐amino‐3‐( p ‐tolyl)‐1,2,4‐triazine‐5(2 H )‐thione ( 4c ) with 2 H ‐1,3‐oxazine‐2,6(3 H )‐dione ( 7 ) the first representative of the 1,2,4‐triazino‐[5,6‐ b ][1,4]diazepin‐8‐ones 8 was obtained.