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Thiazolderivate, VI. Darstellung von Thiazolo[4,5‐ d ]‐ v ‐triazin‐7(6 H )‐onen
Author(s) -
Wobig Dieter
Publication year - 1984
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198419841210
Subject(s) - chemistry , thiazole , medicinal chemistry , nitrous acid , triazine , stereochemistry , organic chemistry
Thiazole Derivatives, VI. — Synthesis of thiazolo[4,5‐ d ]‐ v ‐triazin‐7(6 H )‐ones The 2‐alkylthio‐, 2‐alkylamino‐, 2‐anilino‐, and 2‐( N ‐methylanilino)‐4‐amino‐5‐thiazolecarboxamides 1a – j react with nitrous acid to give the thiazolo[4,5‐ d ]‐ v ‐triazine‐7(6 H )‐ones 2a – j . The compounds 2a and 2d can be methylated in position 6.