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Beitrag zur Synthese von 8‐Azaprostanoiden: Umsetzung von Succinimiden mit (Benzoylmethylen)triphenylphosphoran
Author(s) -
Flitsch Wilhelm,
Jermann Franz
Publication year - 1984
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198419841115
Subject(s) - succinimides , chemistry , succinimide , synthon , medicinal chemistry , stereochemistry , organic chemistry
Contribution to the Synthesis of 8‐Azaprostanoids: Reaction of Succinimides with (Benzoylmethylene)triphenylphosphorane 5‐(2‐Oxo‐2‐phenylethylidene)‐2‐pyrrolidinone ( 4 ), which can easily be transformed into the 8‐azaprostanoid synthon 2 was obtained in a simple way from a reaction of succinimide or thiosuccinimide with (benzoylmethylene)triphenylphosphorane.