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Synthese von rac ‐4′‐ O ‐Methylglabridin, einem antimikrobiellen prenylierten Isoflavan aus Glycyrrhiza glabra L.
Author(s) -
Vermes Borbála,
Antus Sándor,
Gottsegen Ágnes,
Nógrádi Mihály
Publication year - 1983
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198319831119
Subject(s) - chemistry , glycyrrhiza , medicine , pathology , alternative medicine
Synthesis of rac ‐4′‐O‐Methylglabridin, an Antimicrobial Prenylated Isoflavan from Glycyrrhiza glabra L. A synthesis of racemic ‐4′‐ O ‐methylglabridin ( 1 ) is described. The key steps are the transformation of the isoflavan‐4‐one 4 into a dithioacetal 5 followed by desulfuration with Raney nickel.
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