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Umwandlung phenolischer α‐Aminosäuren in α‐Ketosäuren
Author(s) -
Klein Christian,
Schulz Günter,
Steglich Wolfgang
Publication year - 1983
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198319830918
Subject(s) - chemistry , pyruvic acid , dihydroxyphenylalanine , tyrosine , amino acid , trifluoromethyl , organic chemistry , stereochemistry , biochemistry , dopamine , alkyl , neuroscience , biology
Conversion of Phenolic α‐Amino Acids into α‐Keto acids A one‐pot conversion of tyrosine ( 1a ) and 3,4‐dihydroxyphenylalanine (DOPA) ( 1b ) into 3‐(4‐hydroxyphenyl)pyruvic acid ( 2a ) and 3‐(3,4‐dihydroxyphenyl)pyruvic acid ( 2b ), respectively, via 2‐trifluoromethyl‐3‐oxazolin‐5‐ones 5 is described.