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Einstufige Synthese von 17‐Acetoxy‐6‐methyl‐4,6‐pregnadien‐3,20‐dion (Megestrolacetat) aus 17‐Acetox‐4‐pregnen‐3,20‐dion
Author(s) -
Annen Klaus,
Hofmeister Helmut,
Laurent Henry,
Wiechert Rudolf
Publication year - 1983
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198319830421
Subject(s) - megestrol acetate , chemistry , medicinal chemistry , medicine , cancer
A One‐step Synthesis of 17‐Acetoxy‐6‐methyl‐4,6‐pregnadiene‐3,20‐dione (Megestrol Acetate) from 17‐Acetoxy‐4‐pregnene‐3,20‐dione Starting from 17‐Acetoxy‐4‐pregnene‐3,20‐dione ( 3 ), a one‐step synthesis of megestrol acetate ( 5 ) is described.