Preparation of 3,4‐Dihydroxy‐1‐benzeneethanol: A Reinvestigation | Zendy

Baraldi Pier Giovanni | Zendy; Simoni Daniele | Zendy; Manfredini Stefano | Zendy; Menziani Emilia | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Preparation of 3,4‐Dihydroxy‐1‐benzeneethanol: A Reinvestigation

Author(s) -

Baraldi Pier Giovanni,

Simoni Daniele,

Manfredini Stefano,

Menziani Emilia

Publication year - 1983

Publication title -

liebigs annalen der chemie

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 0170-2041

DOI - 10.1002/jlac.198319830417

Subject(s) - chemistry , phenol , organic chemistry , reduction (mathematics) , combinatorial chemistry , medicinal chemistry , stereochemistry , mathematics , geometry

A reinvestigation of the two known methods of preparation of the title compound 1 revealed that one of these leads to a mixture of 1 and 4‐[2‐(acetoxy)ethyl]‐1,2‐benzenediol ( 5 ). The other method yields only 2‐methoxy‐4‐(2‐phenylethyl)phenol ( 6 ). An unambiguous straightforward preparation of 1 by LiAlH 4 reduction of 3,4‐dihydroxy‐1‐benzeneacetic acid ( 8 ) is described.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research