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Addition von Organomagnesiumhalogeniden an C = C‐Bindungen, XVI. Notiz über eine Chrysanthemsäure‐Synthese
Author(s) -
Lehmkuhl Herbert,
Mehler Klaus
Publication year - 1982
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198219821215
Subject(s) - chemistry , adduct , bromide , halide , medicinal chemistry , hydrolysis , organic chemistry
Addition of Organomagnesium Halides to C = C Bonds, XVI 1) . — A Synthetic Route to Chrysanthemic Acid Addition of 1‐isobutenylmagnesium bromide ( 4 ) to 3,3‐dimethylcyclopropene leads to the formation of a 1:1 product as well as considerable amounts of 1:2, 1:3, and higher molecular adducts. Further reaction with carbon dioxide gives, after hydrolysis, a mixture of cis ‐chrysanthemic acid (6; 39%) and the higher molecular acids 1 and 2 .