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Focal cerebellar infarction as an initial sign of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes
Author(s) -
Ko Ara,
Lee SangJun,
Lee YoungMock
Publication year - 2019
Publication title -
journal of inherited metabolic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 102
eISSN - 1573-2665
pISSN - 0141-8955
DOI - 10.1002/jimd.12020
Subject(s) - lactic acidosis , mitochondrial myopathy , medicine , encephalopathy , stroke (engine) , melas syndrome , magnetic resonance imaging , infarction , pathology , myopathy , cerebral infarction , cardiology , radiology , ischemia , biology , mitochondrial dna , myocardial infarction , mechanical engineering , biochemistry , gene , engineering
Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS) is a type of mitochondrial disorder and stroke‐like lesions are observed prominently in the brain magnetic resonance imaging. Those stroke‐like lesions of MELAS patients are usually located in the posterior quadrants and do not correspond to typical vascular territories. This case illustrates that focal cerebellar infarction can be the sole initial sign of MELAS.