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Comment on “The impact of penicillin skin testing on clinical practice and antimicrobial stewardship”
Author(s) -
Khalib Khairin E. M.,
Keogan Mary
Publication year - 2014
Publication title -
journal of hospital medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.128
H-Index - 65
eISSN - 1553-5606
pISSN - 1553-5592
DOI - 10.1002/jhm.2123
Subject(s) - medicine , antimicrobial stewardship , penicillin , antimicrobial , clinical practice , intensive care medicine , family medicine , antibiotics , microbiology and biotechnology , antibiotic resistance , biology
They showed convincing evidence that with a negativepenicillin skin test, a course of b-lactam is safe 2hours after a negative challenge. However, we advisecaution in generalizing these data to the outpatientsetting where resensitization is a possibility. One studyshowed that 4.9% of patients who had negative skintests and drug challenges reacted on rechallenges 3weeks later.