A case of anaphylaxis after a proven penicillin tolerance | Zendy

Rimawi Ramzy H. | Zendy

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A case of anaphylaxis after a proven penicillin tolerance

Author(s) -

Rimawi Ramzy H.

Publication year - 2014

Publication title -

journal of hospital medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.128

H-Index - 65

eISSN - 1553-5606

pISSN - 1553-5592

DOI - 10.1002/jhm.2117

Subject(s) - medicine , penicillin , anaphylaxis , penicillin allergy , medline , intensive care medicine , immunology , dermatology , allergy , antibiotics , microbiology and biotechnology , biology , political science , law

Mohamed-Kalib et al. illustrate 2 important caveatsto penicillin skin testing (PST): (1) there is an excep-tionally rare potential for resensitization, a phenom-enon in which a previously reactive patient is proventolerant, then develops sensitivity and has a positivePST; (2) consider repeating PST prior to a parenteralb-lactam prescription in patients who previouslyreported severe anaphylactic reactions.Our negative predictive value of 100% does notabate the tentative concern for resensitization.

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