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Hyponatremia in cirrhosis
Author(s) -
Sigal Samuel H.
Publication year - 2012
Publication title -
journal of hospital medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.128
H-Index - 65
eISSN - 1553-5606
pISSN - 1553-5592
DOI - 10.1002/jhm.1915
Subject(s) - hyponatremia , medicine , cirrhosis , spontaneous bacterial peritonitis , hepatorenal syndrome , gastroenterology , hepatic encephalopathy , paracentesis , ascites , intensive care medicine
Hyponatremia is common in patients with cirrhosis. Portal hypertension, diuretics, large volume paracentesis without albumin, infection, and multiple medications are connected with the development or worsening of hyponatremia. Hyponatremia in cirrhosis, particularly advanced cirrhosis, is a common development. 1 In a population survey of 997 patients with cirrhosis, 486 (49.4%) and 211 (21.6%) had a serum sodium concentration ([Na + ]) <135 mEq/L and ≤130 mEq/L, respectively. 2 Hyponatremia and its severity correlate with the presence of severe complications of cirrhosis such as hepatorenal syndrome, encephalopathy, and spontaneous bacterial peritonitis. The presence of hyponatremia frequently complicates the management of the cirrhotic patient. Journal of Hospital Medicine 2012; 7:S14–S17. © 2012 Society of Hospital Medicine