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Water‐promoted Dowex 50W catalyzed highly efficient green protocol for 2‐arylbenzothiazole formation
Author(s) -
Mukhopadhyay Chhanda,
Datta Arup
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.9
Subject(s) - chemistry , anhydrous , aryl , catalysis , aqueous medium , aqueous solution , combinatorial chemistry , organic chemistry , alkyl
2‐Aminothiophenol and a variety of aryl aldehydes were allowed to react in one‐pot operation to give 2‐aryl‐benzothiazoles in excellent yields in the presence of Dowex 50W in water. Very high yields coupled with the ease of work‐up procedure, formation of no side products, employment of “reusable” catalyst, and “green” synthesis in aqueous medium without maintaining anhydrous reaction conditions are the most important aspects of this methodology. J. Heterocyclic Chem., (2009).