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(Bromodimethyl)sulfonium Bromide Catalyzed Solvent‐Free Friedlander Synthesis of Substituted Quinolines
Author(s) -
Venkatesham R.,
Manjula A.,
Vittal Rao B.
Publication year - 2012
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.873
Subject(s) - chemistry , sulfonium , bromide , catalysis , methylene , condensation , solvent , organic chemistry , combinatorial chemistry , salt (chemistry) , physics , thermodynamics
A simple and efficient (bromodimethyl)sulfonium bromide catalyzed synthesis of quinolines, by condensation of α‐amino carbonyl, that is, 2‐aminobenzophenone and 2‐aminoacetophenone with α‐methylene containing carbonyl like 1,3‐dicarbonyls has been developed. The reaction is versatile, solvent‐free protocol for generation of structurally diverse quinolines.