Chemoselectivity of 2‐Arylmethyleneaminoisoindolin‐1,3‐diones toward Arenes under Friedel–Crafts Conditions: An Efficient Synthesis of Benzophenones Integrated with 2‐Substituted Hydrazone Moieties | Zendy

Derbala Hamed A. | Zendy

Premium

Chemoselectivity of 2‐Arylmethyleneaminoisoindolin‐1,3‐diones toward Arenes under Friedel–Crafts Conditions: An Efficient Synthesis of Benzophenones Integrated with 2‐Substituted Hydrazone Moieties

Author(s) -

Derbala Hamed A.

Publication year - 2012

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.854

Subject(s) - chemistry , chemoselectivity , hydrazone , friedel–crafts reaction , aryl , proton nmr , organic chemistry , catalysis , mass spectrum , carbon 13 nmr , medicinal chemistry , ion , alkyl

Treatment 2‐arylmethyleneaminoisoindole‐1,3‐diones 1a – c with arenes in the presence of AlCl 3 ‐DMF complex as a catalyst afforded the novel compounds, 2‐((arylidenehydrazono)(aryl)‐methyl)benzophenones 3a – n in satisfactory yields. The structure of the obtained products 3a – n was confirmed by the use of IR, 1 H‐NMR, 13 C‐NMR, mass spectra, and elemental analyses.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research