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New dihydro‐1,2,4‐triazolo[1,5‐ a ]pyrimidines based on arylidene derivatives of 5‐acetylbarbituric and dehydroacetic acids
Author(s) -
Rudenko Roman V.,
Komykhov Sergey A.,
Musatov Vladimir I.,
Desenko Sergey M.
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.81
Subject(s) - chemistry , dehydroacetic acid , barbituric acid , triazole , organic chemistry , medicinal chemistry
The reaction of 3‐amino‐1,2,4‐triazole ( 1 ) with arylidene‐5‐acetyl barbituric acid ( 2b , 2c ) or dehydroacetic acid ( 2a ) by refluxing in butanol leads to the formation of dihydro‐1,2,4‐triazolo[1,5‐ a ]pyrimidines 3a , 3b , 3c . J. Heterocyclic Chem., 46 , 285 (2009).