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Synthesis and transformations of hydrazine substituted 6‐fluoro derivatives of 1,3,4‐thiadiazolo[3,2‐ a ]pyrimidine
Author(s) -
Kukaniev Muhamadsho A.,
Párkányi Cyril
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.773
Subject(s) - chemistry , hydrazine (antidepressant) , pyrimidine , alkyl , medicinal chemistry , organic chemistry , stereochemistry , chromatography
2‐Alkyl and 2‐arylhydrazine derivatives of 5 H ‐2‐R‐6‐fluoro‐7‐methyl‐1,3,4‐thiadiazolo[3,2‐ a ]pyrimidin‐5‐one were prepared by reaction of 5 H ‐2‐bromo‐6‐fluoro‐7‐methyl‐1,3,4‐thiadiazolo[3,2‐ a ]pyrimidin‐5‐one with hydrazine derivatives. A convenient procedure was developed for the preparation of new hydrazine derivatives of 5 H ‐2‐R‐6‐fluoro‐7‐methyl‐1,3,4‐thiadiazolo[3,2‐ a ]pyrimidin‐5‐one. J. Heterocyclic Chem., (2011).

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