Synthesis of Some New Heterocycles Derived from Ethyl 7‐Amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5 H ‐thiazolo[3,2‐ a ]pyrimidine‐6‐carboxylate of Biological Importance | Zendy

Youssef Mohamed Salah K. | Zendy; Abbady Mohamed S. | Zendy; Ahmed Ragaa A. | Zendy; Omar Ahmed A. | Zendy

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Synthesis of Some New Heterocycles Derived from Ethyl 7‐Amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5 H ‐thiazolo[3,2‐ a ]pyrimidine‐6‐carboxylate of Biological Importance

Author(s) -

Youssef Mohamed Salah K.,

Abbady Mohamed S.,

Ahmed Ragaa A.,

Omar Ahmed A.

Publication year - 2013

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.735

Subject(s) - chemistry , ethyl cyanoacetate , reagent , pyrimidine , aryl , pyrazoline , medicinal chemistry , organic chemistry , stereochemistry , malononitrile , catalysis , alkyl

Ethyl 7‐amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5 H ‐thiazolo[3,2‐ a ]pyrimidine‐6‐carboxylate was synthesized by the reaction of 4‐(2‐aminothiazol‐4‐yl)‐3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazoline with arylidene ethyl cyanoacetate and it transformed to related fused heterocyclic systems via reaction with various reagents. The biological activities of these compounds were evaluated.

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