Premium
Synthesis, characterization, and evaluation of antimicrobial activities of a new class of macrocyclic phosphonates
Author(s) -
Chandra Sekhar Reddy G.,
Uma Ravi Sankar A.,
Veera Narayana Reddy M.,
Radha Rani C.,
Suresh Reddy C.
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.727
Subject(s) - chemistry , antimicrobial , characterization (materials science) , combinatorial chemistry , class (philosophy) , organic chemistry , nanotechnology , artificial intelligence , materials science , computer science
A series of a new class of phosphorus analogue macrocycles was accomplished by condensation of N‐substituted‐[bis(3,5‐dimethyl‐2‐hydroxybenzyl)]‐amines with various phosphorus dichlorides in dry toluene in the presence of triethylamine at 0–50°C. All the title compounds were evaluated for antimicrobial activity to determine their efficacy and were effective in suppressing the growth of bacteria and fungi. The chemical structures of the title products were characterized by IR, 1 H, 13 C, 31 P‐NMR, mass spectral studies, and elemental analysis. J. Heterocyclic Chem., (2011).