An efficient synthesis of 2,3,4‐trisubstituted quinolines through alkynylation‐cyclization at ambient temperature | Zendy

Patil Dipti R. | Zendy; Salunkhe Sonali M. | Zendy; Deshmukh Madhukar B. | Zendy; Anbhule Prashant V. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

An efficient synthesis of 2,3,4‐trisubstituted quinolines through alkynylation‐cyclization at ambient temperature

Author(s) -

Patil Dipti R.,

Salunkhe Sonali M.,

Deshmukh Madhukar B.,

Anbhule Prashant V.

Publication year - 2011

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.715

Subject(s) - chemistry , quinoline , zwitterion , alkynylation , pyridine , dimethyl acetylenedicarboxylate , organic chemistry , acetylenedicarboxylate , combinatorial chemistry , medicinal chemistry , catalysis , molecule , cycloaddition

A series of 2,3,4‐trisubstituted quinoline derivatives have been synthesized by reactions between 2‐aminoaryl ketones and dialkyl acetylenedicarboxylate. The synthetic pathway allows for the direct construction of said quinoline derivatives in pyridine/ethanol at ambient temperature through a zwitterion intermediate. J. Heterocyclic Chem., (2011)

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research