Synthesis and α‐glucosidase inhibitory, DPPH scavenging activity of substituted 2‐oxo‐2 H ‐chromen‐7‐yl‐dihydrogen phosphate derivatives | Zendy

Kumar J. Ashok | Zendy; Tiwari Ashok K. | Zendy; Ali A.Zehra | Zendy; Rao R. Ranga | Zendy; Raju B. China | Zendy

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Synthesis and α‐glucosidase inhibitory, DPPH scavenging activity of substituted 2‐oxo‐2 H ‐chromen‐7‐yl‐dihydrogen phosphate derivatives

Author(s) -

Kumar J. Ashok,

Tiwari Ashok K.,

Ali A.Zehra,

Rao R. Ranga,

Raju B. China

Publication year - 2011

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.675

Subject(s) - chemistry , coumarin , dpph , scavenging , phosphate , condensation , organic chemistry , nuclear chemistry , phosphorylation , medicinal chemistry , antioxidant , biochemistry , physics , thermodynamics

Series of phosphorylated coumarin derivatives ( 4a , 4b , 4c , 4d , 4e , 4f , 4g , 4h , 4i , 4j ) were synthesized by Pechmann condensation , phosphorylation , and debenzylation reactions in very good yields. Thus, synthesized compounds ( 4a , 4b , 4c , 4d , 4e , 4f , 4g , 4h , 4i , 4j ) were evaluated for their α‐glucosidase and 1,1‐diphenyl‐2‐picrylhydrazyl scavenging activities; few compounds showed moderate to good activity. J. Heterocyclic Chem., 00 , 00 (2011).

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