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Synthesis and antimicrobial activity of substituted [(pyrazol‐4‐yl)methylene]hydrazono‐2,3‐dihydrothiazoles and their sugar derivatives
Author(s) -
AbdelRahman Adel A.H.,
ElSayed Wael A.,
Zaki ElSayed G.,
Mohamed Asem A.,
Fadda Ahmed A.
Publication year - 2012
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.668
Subject(s) - chemistry , methylene , antimicrobial , hydrazone , sugar , organic chemistry , glycoside , medicinal chemistry , stereochemistry
A number of new [(pyrazol‐4‐yl)methylene]hydrazono‐2,3‐dihydrothiazole derivatives, their sugar hydrazones and N ‐glycosides were synthesized. Furthermore, N ‐substituted oxygenated alkyl and hydroxyl derivatives and 1,3,4,‐oxadiazoline acyclic nucleoside analogs were prepared. The newly synthesized compounds were tested for their antimicrobial activities and showed moderate to high inhibition activities. J. Heterocyclic Chem., (2012).