z-logo
Premium
Synthesis and antibacterial activity of novel series of 2‐( p ‐tolyloxy)‐3‐(5‐(pyridin‐4‐yl)‐1,3,4‐oxadiazol‐2‐yl)quinoline
Author(s) -
Joshi Ratnadeep S.,
Mandhane Priyanka G.,
Khan Wajid,
Gill Charansingh H.
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.653
Subject(s) - chemistry , quinoline , antibacterial activity , methylene , proton nmr , stereochemistry , elemental analysis , medicinal chemistry , combinatorial chemistry , organic chemistry , bacteria , genetics , biology
A new series of 2‐( p ‐tolyloxy)‐3‐(5‐(pyridin‐4‐yl)‐1,3,4‐oxadiazol‐2‐yl)quinoline were synthesized from oxidative cyclization of N ′‐((2‐( p ‐tolyloxy)quinoline‐3‐yl)methylene)isonicotinohydrazide in DMSO/I 2 at reflux condition for 3–4 h. The structures of the new compounds were confirmed by elemental analyses as well as IR, 1 H‐NMR, and mass spectral data. All the synthesized compounds were screened for their antibacterial activities against various bacterial strains. Several of these compounds showed potential antibacterial activity . J. Heterocyclic Chem., (2011).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here