Synthesis and  antibacterial activity  of novel series of 2‐( p ‐tolyloxy)‐3‐(5‐(pyridin‐4‐yl)‐1,3,4‐oxadiazol‐2‐yl)quinoline | Zendy

Joshi Ratnadeep S. | Zendy; Mandhane Priyanka G. | Zendy; Khan Wajid | Zendy; Gill Charansingh H. | Zendy

Premium

Synthesis and antibacterial activity of novel series of 2‐( p ‐tolyloxy)‐3‐(5‐(pyridin‐4‐yl)‐1,3,4‐oxadiazol‐2‐yl)quinoline

Author(s) -

Joshi Ratnadeep S.,

Mandhane Priyanka G.,

Khan Wajid,

Gill Charansingh H.

Publication year - 2011

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.653

Subject(s) - chemistry , quinoline , antibacterial activity , methylene , proton nmr , stereochemistry , elemental analysis , medicinal chemistry , combinatorial chemistry , organic chemistry , bacteria , genetics , biology

A new series of 2‐( p ‐tolyloxy)‐3‐(5‐(pyridin‐4‐yl)‐1,3,4‐oxadiazol‐2‐yl)quinoline were synthesized from oxidative cyclization of N ′‐((2‐( p ‐tolyloxy)quinoline‐3‐yl)methylene)isonicotinohydrazide in DMSO/I 2 at reflux condition for 3–4 h. The structures of the new compounds were confirmed by elemental analyses as well as IR, 1 H‐NMR, and mass spectral data. All the synthesized compounds were screened for their antibacterial activities against various bacterial strains. Several of these compounds showed potential antibacterial activity . J. Heterocyclic Chem., (2011).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research