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An efficient one‐pot synthesis of bis‐indolylmethanes containing pyrazolyl catalyzed by Brønsted acidic ionic liquid under solvent‐free conditions
Author(s) -
Liu Chenjiang,
Yu Chuanji
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.650
Subject(s) - chemistry , ionic liquid , catalysis , pyrazole , solvent , condensation , organic chemistry , ionic bonding , reaction conditions , ion , physics , thermodynamics
Brønsted acidic ionic liquid [PyNCH 2 CO 2 H][HSO 4 ] was found to be an effective catalyst for the condensation reactions of indoles with various 4‐formylpyrazoles to afford the corresponding bis‐indolylmethanes containing pyrazole under solvent‐free conditions. The satisfactory results were obtained with excellent yields, short reaction time, and simplicity in the experimental procedure. J. Heterocyclic Chem., (2011).