Behavior of 2‐iminothiazolidin‐4‐one with different reagents | Zendy

Hamama Wafaa S. | Zendy; Ismail Mohadamed A. | Zendy; Soliman Mamdoh | Zendy; Shaaban Saad | Zendy; Zoorob Hanafi H. | Zendy

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Behavior of 2‐iminothiazolidin‐4‐one with different reagents

Author(s) -

Hamama Wafaa S.,

Ismail Mohadamed A.,

Soliman Mamdoh,

Shaaban Saad,

Zoorob Hanafi H.

Publication year - 2011

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.628

Subject(s) - chemistry , formylation , electrophile , reagent , cycloaddition , benzene , organic chemistry , medicinal chemistry , combinatorial chemistry , catalysis

Annulations of 2‐imino‐4‐thiazolidinone ( 5 ) via cycloaddition followed by cyclocondensation reaction with 1,3‐diphenylpropenone ( 6 ), benzylidenemalonate, and 1,2‐bis(chloromethyl)benzene gave 7 , 19 and 20 , respectively. Reaction of 5 with suitable electrophiles (Mannich bases of arylalkanone), 1,4‐dichlorobenzene (diarylmethylation), and formylation afforded 8 / 9 , 21 / 22 , and 23 , respectively. J. Heterocyclic Chem., (2011).

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