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Novel catalytic bromolactonization of alkenoic acids using iodobenzene and Oxone®
Author(s) -
He Yan,
Pu Ye,
Shao Bo,
Yan Jie
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.617
Subject(s) - iodobenzene , chemistry , catalysis , organic chemistry , bromide , reaction conditions , combinatorial chemistry
The novel catalytic reaction for bromolactonization of alkenoic acids is reported. When iodobenzene is used as recyclable catalyst in combination with Oxone® as terminal oxidant, the cyclization of various 4‐pentenoic acids with sodium bromide is easily carried out in CF 3 CH 2 OH at room temperature and giving five‐membered bromolactones in good yields. J. Heterocyclic Chem., 2011.