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A simple, diversity oriented synthesis of highly substituted pyridines
Author(s) -
Kaczanowska Katarzyna,
Eickhoff Holger,
Albert Klaus,
Wiesmüller KarlHeinz,
Schaffner ArnaudPierre
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.614
Subject(s) - chemistry , aryl , simple (philosophy) , combinatorial chemistry , condensation , condensation reaction , organic chemistry , computational chemistry , catalysis , alkyl , physics , epistemology , thermodynamics , philosophy
A particularly straightforward and efficient protocol for the synthesis of highly substituted pyridines , based on a condensation reaction of β‐aminocrotonitrile and easily accessible ( E )‐2‐oxo‐4‐aryl‐but‐3‐enoic acids and ( E )‐4‐oxo‐4‐aryl‐but‐2‐enoic acids is described. J. Heterocyclic Chem., (2011).
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