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An expeditious one‐pot synthesis of substituted phenylazetidin‐2‐ones in the presence of zeolite
Author(s) -
Pagadala Ramakanth,
Meshram Jyotsna S.,
Chopde Himani N.,
Jetti Venkateshwarlu,
Udayini V.
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.604
Subject(s) - chemistry , zeolite , microwave irradiation , catalysis , chloride , organic chemistry , antibacterial activity , antimicrobial , acetyl chloride , nuclear chemistry , bacteria , biology , genetics
In this study, one‐pot rapid and efficient series of phenylazetidin‐2‐ones were synthesized from N,N‐dimethylaminobenzaldehyde, different substituted aromatic amines and phenylacetyl chloride in the presence of zeolite catalyst under microwave irradiation. We also reported schiff bases (1a–j) by classical and conventional microwave technique. The titled compounds are evaluated for their antimicrobial properties . The activities are due to CO, CN, linkages in 2‐azetidinones. All the compounds have shown comparable antibacterial activities. J. Heterocyclic Chem., (2011).