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Microwave‐assisted expeditious synthesis of novel benzo[ b ][1,8]‐naphthyridine‐3‐carbonitriles
Author(s) -
Singh Satish Kumar,
Singh Krishnd
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.595
Subject(s) - chemistry , sulfanyl , microwave irradiation , dichloromethane , anhydrous , cyclohexanone , organic chemistry , combinatorial chemistry , medicinal chemistry , catalysis , solvent
A rapid and facile method for the synthesis of novel 5‐amino‐2‐sulfanyl tetrahydrobenzo[ b ][1,8]‐naphthyridine‐3‐carbonitrile derivatives has been developed by the treatment of 2‐amino‐3,5‐dicarbonitrile‐6‐sulfanyl pyridines with cyclohexanone in the presence of anhydrous aluminium chloride in dry dichloromethane under controlled microwave irradiation. J. Heterocyclic Chem., 00 , 00 (2011).