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An efficient synthesis of 2,3‐dihydroquinazolin‐4(1 H )‐one derivatives under catalyst‐free and solvent‐free conditions
Author(s) -
Gao Lijiu,
Ji Honglou,
Rong Liangce,
Tang Dan,
Zha Yunyun,
Shi Yanhui,
Tu Shujiang
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.592
Subject(s) - chemistry , catalysis , ammonium acetate , organic chemistry , reaction conditions , solvent , combinatorial chemistry , high performance liquid chromatography
A simple, efficient and convenient one‐pot synthesis of 2,3‐dihydroquinazolin‐4(1 H )‐one derivatives under solvent‐free and catalyst‐free conditions by the reaction of aromatic aldehydes, isatoic anhydride, and ammonium acetate was reported. The advantages of this protocol include short reaction time, mild reaction conditions, easy work‐up, high yields, and environmental friendliness. J. Heterocyclic Chem., (2011).

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