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Green and efficient synthesis of pyrazolo[3,4‐ b ]quinolin‐5‐ones derivatives by microwave‐assisted multicomponent reaction in hot water medium
Author(s) -
Andriushchenko Anastasiya Yu.,
Desenko Sergey M.,
Chernenko Vitaliy N.,
Chebanov Valentin A.
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.586
Subject(s) - dimedone , chemistry , microwave , environmentally friendly , combinatorial chemistry , component (thermodynamics) , reaction conditions , organic chemistry , catalysis , biology , ecology , physics , thermodynamics , quantum mechanics
Novel simple, efficient, and eco‐friendly synthetic procedure for preparation of pyrazolo[3,4‐b]quinolin‐5‐ones based on three‐component microwaves‐assisted heterocyclization reaction of 5‐aminopyrazoles, aromatic aldehydes, and dimedone in hot‐water medium was developed. The new method allows obtaining target heterocycles in good and excellent yields and with high degree of purity. J. Heterocyclic Chem., (2011).