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Synthesis of new polydentate pyrazolyl‐ethene ligands by interaction of 1 H ‐pyrazole and 1,1,2,2‐tetrabromoethane in a superbasic medium
Author(s) -
Potapov Andrei S.,
Nudnova Evgenia A.,
Khlebnikov Andrei I.,
Ogorodnikov Vladimir D.,
Petrenko Tatiana V.
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.566
Subject(s) - chemistry , pyrazole , reagent , medicinal chemistry , denticity , potassium hydroxide , potassium , crystal structure , tris , organic chemistry , biochemistry
Reaction of pyrazole and 1,1,2,2‐tetrabromoethane in a superbasic medium dimethylsulfoxide‐potassium hydroxide was investigated, and a number of pyrazolyl‐ and bromo‐substituted ethenes, which are the products of concurrent substitution and elimination reactions , were identified. Carrying out the reaction using different reagent mole ratios allowed to selectively isolate Z ‐1,2‐bis(pyrazol‐1‐yl)ethene, 1,1,2‐tris(pyrazol‐1‐yl)ethane, and 1,1,2,2‐tetrakis(pyrazol‐1‐yl)ethane. Crystal structure of { Z ‐1,2‐bis (pyrazol‐1‐yl)ethene}dichlorozinc was established using X‐ray diffraction method. J. Heterocyclic Chem., (2011).