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A solvent‐free protocol for one pot conversion of Baylis Hillman acetates to pyridopyrimidinones
Author(s) -
Sreevani R.,
Manjula A.,
Rao B. Vittal
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.560
Subject(s) - chemistry , pyridine , solvent , organic chemistry , baylis–hillman reaction , transformation (genetics) , combinatorial chemistry , catalysis , biochemistry , gene
A facile one pot transformation of Baylis Hillman acetates to pyrido[1,2‐a]pyrimidin‐2‐ones by reaction with 2‐amino pyridine in a total solvent‐free protocol is illustrated. The 3‐substituted‐2H‐pyrido[1,2‐a]pyrimidin‐2‐ones are obtained in pure form without involving any purification technique or solvent. J. Heterocyclic Chem., (2011).

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