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Application of the acetate of baylis‐hillman adducts of salicylaldehydes in the synthesis of methyl 2‐oxo‐2,3‐dihydrobenzo[ b ]oxepine‐4‐carboxylates
Author(s) -
Ahn SangHyun,
Lim Hee Nam,
Lee KeeJung
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450622
Subject(s) - chemistry , cyanation , adduct , acetylation , organic chemistry , phosphomolybdic acid , stereochemistry , catalysis , biochemistry , gene
A simple synthesis of several methyl 2‐oxo‐2,3‐dihydrobenzo[ b ]oxepine‐4‐carboxylates from Baylis‐Hillman adducts of O ‐benzyl protected 2‐hydroxybenzadehydes has been described through the acetylation, cyanation, debenzylation, as well as acid assisted Pinner cyclization.