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Solvent‐free synthesis of 5‐methyl‐7‐aryl‐4,7‐dihydrotetrazolo[1,5‐ a ]pyrimidine‐6‐carboxylic esters catalyzed by sulfamic acid
Author(s) -
Yao Changsheng,
Lei Song,
Wang Cuihua,
Yu Chenxia,
Tu Shujiang
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450609
Subject(s) - chemistry , sulfamic acid , catalysis , aryl , pyrimidine , solvent , organic chemistry , carboxylic acid , stereochemistry , alkyl
The solvent‐free synthesis of 5‐methyl‐7‐aryl‐4,7‐dihydrotetrazolo[1,5‐ a ]pyrimidine‐6‐carboxylic esters was performed and effectively catalyzed by sulfamic acid. Compared with conventional methods, this protocol features mild reaction conditions and high yields. Furthermore, it is solvent‐free and thus eco‐friendly.