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Synthesis of new bis‐3,5‐diphenylpyrazolines derivatives linked with alkyl chains
Author(s) -
Insuasty Braulio,
Martinez Henry,
Quiroga Jairo,
Abonía Rodrigo,
Nogueras Manuel,
Cobo Justo
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450547
Subject(s) - chemistry , alkyl , hydrazine (antidepressant) , acetic acid , organic chemistry , medicinal chemistry , biochemistry
New bis‐3,5‐diphenylpyrazoline derivatives have been synthesized according to Elway [1] (1999) and Sangwan's[2] (1992) methodology. Most of them were obtained in good yields, from the reaction between an alkyl linked bis‐chalcones and hydrazine in acetic acid. The activity of some bis‐pyrazolines was evaluated against Helicobacter pylori.