Premium
An efficient and green synthesis of 3,3′‐benzylidenebis (4‐hydroxy‐6‐methylpyridin‐2(1 H )‐one) derivatives through multi‐component reaction in ionic liquid
Author(s) -
Shi Daqing,
Ji Shunjun,
Shi Daqing,
Ni Sainan,
Yang Fang
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450503
Subject(s) - chemistry , ionic liquid , aldehyde , aniline , ammonium acetate , component (thermodynamics) , ammonium , organic chemistry , reaction conditions , high performance liquid chromatography , catalysis , physics , thermodynamics
A series of new 3,3′‐benzylidenebis(4‐hydroxy‐6‐methylpyridin‐2(1 H )‐one) derivatives were synthesized via a three‐component reaction of an aldehyde, an aniline or ammonium acetate and 6‐methyl‐4‐hydroxypyran‐2‐one in ionic liquid. These heterocyclic compounds produced could be conveniently separated from the reaction mixture without any volatile organic solvents, and the ionic liquid could be readily reused without efficiency loss after simple treatment.