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Synthesis of new imidazole derivatives
Author(s) -
Nowak Krystyna,
Szpakiewicz Barbara
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450453
Subject(s) - chemistry , imidazole , alkyl , nitroimidazole , combinatorial chemistry , stereochemistry , organic chemistry
The derivatives of 1‐propyl‐ and 1‐butyl‐ of 2‐methyl‐5‐nitroimidazole containing phenylpiperazine, m ‐chloro‐ and o ‐methoxyphenylpiperazine attached at the end of alkyl chain were synthesed. For the obtained new compounds, the biological activity was predicted using the computer program PASS.