Preparation of derivatives of 1‐(2‐pyrimidinyl)piperazine as potential antianxiety, antidepressant, and antipsychotic agents | Zendy

Becker Irwin | Zendy

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Preparation of derivatives of 1‐(2‐pyrimidinyl)piperazine as potential antianxiety, antidepressant, and antipsychotic agents

Author(s) -

Becker Irwin

Publication year - 2008

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570450410

Subject(s) - piperazine , chemistry , antidepressant , antipsychotic , solvent , pharmacology , organic chemistry , psychiatry , schizophrenia (object oriented programming) , psychology , medicine , anxiety

This paper describes the preparation of twenty‐eight derivatives of 1‐(2‐pyrimidinyl)piperazine as potential antianxiety, antidepressant, and antipsychotic agents. In twenty‐six of the preparations a chloro nitrogen heterocycle was caused to react with an excess of 1‐(2‐pyrimidinyl)piperazine in the absence of solvent. A specific example is given above.

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