A new, efficient and chemoselective one‐pot protocol for synthesis of 4‐arylidene‐2‐phenyl‐5(4 H )‐oxazolones from aryl aldehyde bisulfite adducts promoted by POCL 3 | Zendy

Khosropour Ahmad R. | Zendy; Khodaei Mohammad M. | Zendy; Jomor Seyed J. Hoseini | Zendy

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A new, efficient and chemoselective one‐pot protocol for synthesis of 4‐arylidene‐2‐phenyl‐5(4 H )‐oxazolones from aryl aldehyde bisulfite adducts promoted by POCL 3

Author(s) -

Khosropour Ahmad R.,

Khodaei Mohammad M.,

Jomor Seyed J. Hoseini

Publication year - 2008

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570450308

Subject(s) - chemistry , aldehyde , chemoselectivity , adduct , aryl , bisulfite , phosphoryl chloride , organic chemistry , chloride , medicinal chemistry , combinatorial chemistry , catalysis , biochemistry , alkyl , gene expression , dna methylation , gene

A one‐pot procedure for the synthesis of 4‐arylidene‐2‐phenyl‐5(4 H )oxazolones directly from aryl aldehyde bisulfite adducts in the absence of Ac 2 O in good to excellent yields using phosphoryl chloride is reported. In addition, the observed chemoselectivity can be considered as a noteworthy advantage of this method.

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