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One‐pot synthesis of angular furocoumarins: A simple protocol involving unprecedented intramolecular aldol condensation
Author(s) -
Dutta Lakshmi Narayan,
De Banani,
Patra Amarendra
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450306
Subject(s) - chemistry , aldol condensation , intramolecular force , anhydrous , acetone , condensation , furocoumarins , aldol reaction , organic chemistry , stereochemistry , photochemistry , catalysis , physics , thermodynamics
Refluxing of hydroxycoumarinyl ketones with methyl γ‐bromocrotonate in dry acetone in presence of anhydrous K 2 CO 3 afforded substituted angelicins (angular furanocoumarins) in satisfactory yields through intramolecular Aldol condensation followed by β‐elimination.